猎奇重口

The NMHPVPR information systems, which are fully electronic, transcend organizational structures of healthcare such as health plan and payers as well as diagnostic laboratory, medical facility and formal or informal community-based health care organizations.

Reporting to the NMHPVPR is conducted at a national, regional and state-wide level and is based at the individual woman and provider levels. By comparison to organizational systems such as Managed Care Organizations (MCO), which suffer both loss from area out-migration and loss to membership due to personal decisions or changes in employer insurance agreements, the NMHPVPR only suffers out-migration from the entire state of New Mexico.

2002

In 2002, Dr. Wheeler, the NM-HOPES-PROSPR Research Center Director was a co-leader of US studies demonstrating successful proof-of-principal efficacy of the monvalent HPV 16 vaccine, the prototype of the Merck Quadrivalent HPV vaccine. During this same period, she was part of the NCI ALTS team demonstrating effective utility of HPV testing in the triage of ASC-US (equivocal) screening Pap tests.

2004

Realizing the directions that cervical cancer prevention would gradually turn toward, in 2004, Dr. Wheeler began working with the New Mexico Department of Health (NM-DOH) to consider the importance of statewide surveillance for cervical screening including Pap and HPV testing and resultant diagnostic and treatment outcomes. Documenting US cervical screening programs would be essential to understanding benefit, harms and effectiveness (including costs) of HPV-based screening innovations but also would be requisite to rational integration of screening and vaccination. Furthermore, without such evidence, both screening and vaccination would be undertaken as if they had no relation to one another, a clinical redundancy of breathtaking expense.

2006

In 2006, after 2 years of important discussions and ground work to demonstrate the feasibility of and capacity for statewide fully electronic surveillance of the cervical screening process, the NM-DOH in partnership with the University of New Mexico (UNM) established the New Mexico HPV Pap Registry (NMHPVPR). Dr. Wheeler , the NM-HOPES-PRC Director championed, created and developed the visionary NMHPVPR which today, under state administrative code (NMAC 7.4.3.12) requires all cervical screening (Papanicolaou (Pap) and HPV tests) as well diagnostic and treatment (all cervical, vulvar and vaginal pathology) to be reported through the .

The NMHPVPR cervical cancer screening and prevention surveillance program was created in the interest of the health of all women to determine the public health significance and cost effectiveness of longitudinal changes in clinical practice impacting HPV-related cervical disease outcomes.

The NMHPVPR was also intended to inform unanticipated or adverse events related to changes in screening and HPV vaccination practices. As a designee of the NM-DOH, the NMHPVPR is an authorized public health authority. The NM-DOH authorizes the NMHPVPR to collect and evaluate data under the Notifiable Diseases and Conditions (NMAC 7.4.3). The NMHPVPR is also authorized to collect and evaluate HPV vaccine administrative data.

Through linkage of HPV vaccine data to the NMHPVPR cervical screening, diagnosis and treatment data, behaviors and outcomes can be monitored in recipients of HPV vaccines.

The NMHPVPR is a one-of-a-kind population-based cervical screening registry with linkages to HPV vaccine administrative data that offers a novel US model for public health surveillance and prevention.

Landy R, Mathews C, Robertson M, Wiggins CL, McDonald YJ, Goldberg DW, Scarinci IC, Cuzick J, Sasieni PD, Wheeler CM.  Gynecol Oncol. 2020 Nov;159(2):344-353. doi: 10.1016/j.ygyno.2020.08.033. Epub 2020 Sep 22. PMID: 32977987

Castle PE, Adcock R, Cuzick J, Wentzensen N, Torrez-Martinez NE, Torres SM, Stoler MH, Ronnett BM, Joste NE, Darragh TM, Gravitt PE, Schiffman M, Hunt WC, Kinney WK, Wheeler CM; New Mexico HPV Pap Registry Steering Committee; p16 IHC Study Panel.  Arch Pathol Lab Med. 2020 Jun;144(6):725-734. doi: 10.5858/arpa.2019-0241-OA. Epub 2019 Nov 13. PMID: 31718233

Drolet M, Bénard É, Pérez N, Brisson M; HPV Vaccination Impact Study Group.  Lancet. 2019 Aug 10;394(10197):497-509. doi: 10.1016/S0140-6736(19)30298-3. Epub 2019 Jun 26. PMID: 31255301

Landy R, Sasieni PD, Mathews C, Wiggins CL, Robertson M, McDonald YJ, Goldberg DW, Scarinci IC, Cuzick J, Wheeler CM; New Mexico HPV Pap Registry Steering Committee.  Int J Cancer. 2019 Dec 13. doi: 10.1002/ijc.32826. [Epub ahead of print. PMID:31837006

Castle PE, Adcock R, Cuzick J, Wentzensen N, Torrez-Martinez NE, Torres SM, Stoler MH, Ronnett BM, Joste NE, Darragh TM, Gravitt PE, Schiffman M, Hunt WC, Kinney WK, Wheeler CM; New Mexico HPV Pap Registry Steering Committee; p16 IHC Study Panel.  Arch Pathol Lab Med. 2019 Nov 13. doi: 10.5858/arpa.2019-0241-OA. [Epub ahead of print] PMID:31718233

Adcock R, Cuzick J, Hunt WC, McDonald RM, Wheeler CM; New Mexico HPV Pap Registry Steering Committee.  Cancer Epidemiol Biomarkers Prev. 2019 Nov;28(11):1816-1824. doi: 10.1158/1055-9965.EPI-19-0239. Epub 2019 Sep 5. PMID:31488417

Kamineni A, Tiro JA, Beaber EF, Silverberg MJ, Wheeler CM, Chao CR, Chubak J, Skinner CS, Corley DA, Kim JJ, Balasubramanian BA, Paul Doria-Rose V; PROSPR consortium.  Int J Cancer. 2019 Mar 15;144(6):1460-1473. doi: 10.1002/ijc.31940. Epub 2018 Dec 20. PMID:30353911

Castle PE, Wheeler CM, Campos NG, Sy S, Burger EA, Kim JJ; New Mexico HPV Pap Registry Steering Committee.  Prev Med. 2018 Jun;111:177-179. doi:10.1016/j.ypmed.2018.03.011. Epub 2018 Mar 14. PMID:29548787

Cuzick J, Myers O, Lee JH, Shi Y, Gage JC, Hunt WC, Robertson M, Wheeler CM; New Mexico HPV Pap Registry Steering Committee.   JAMA Oncol. 2017 Oct 1;3(10):1327-1334. doi: 10.1001/jamaoncol.2017.1040. PMID:28655061

 Habbema D, Weinmann S, Arbyn M, Kamineni A, Williams AE, M C M de Kok I, van Kemenade F, Field TS, van Rosmalen J, Brown ML.  Int J Cancer. 2017 Mar 1;140(5):1215-1222. doi: 10.1002/ijc.30524. PMID: 27864938

Gage JC, Hunt WC, Schiffman M, Katki HA, Cheung LA, Myers O, Cuzick J, Wentzensen N, Kinney W, Castle PE, Wheeler CM; New MexicoHPVPapRegistry Steering Committee.  Obstet Gynecol. 2016 Dec;128(6):1248-1257. PMID:27824767

Benard VB, Castle PE, Jenison SA, Hunt WC, Kim JJ, Cuzick J, Lee JH, Du R, Robertson M, Norville S, Wheeler CM; New MexicoHPVPapRegistry Steering Committee. JAMA Oncol. 2016 Sep 29. doi: 10.1001/jamaoncol.2016.3609. [Epub ahead of print] PMID:27685805

Tosteson AN, Beaber EF, Tiro J, Kim J, McCarthy AM, Quinn VP, Doria-Rose VP, Wheeler CM, Barlow WE, Bronson M, Garcia M, Corley DA, Haas JS, Halm EA, Kamineni A, Rutter CM, Tosteson TD, Trentham-Dietz A, Weaver DL; PROSPR consortium.  J Gen Intern Med. 2016 Apr;31(4):372-9. doi: 10.1007/s11606-015-3552-7. PMID: 26658934 

McDonald YJ, Goldberg DW, Scarinci IC, astle PE, Cuzick J, Robertson M, Wheeler CM.  J Rural Health. 2016 Aug 24. doi: 10.1111/jrh.12202. [Epub ahead of print] PMID:27557124

Gage JC, Hunt WC, Schiffman M, Katki HA, Cheung LC, Cuzick J, Myers O, Castle PE, Wheeler CM; New MexicoHPVPapRegistry Steering Committee.  Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):36-42. doi: 10.1158/1055-9965.EPI-15-0669. Epub 2015 Oct 30. PMID: 26518316 

Kim JJ, Campos NG, Sy S, Burger EA, Cuzick J, Castle PE, Hunt WC, Waxman A, Wheeler CM; New MexicoHPVPapRegistry Steering Committee.  Ann Intern Med. 2015 Oct 20;163(8):589-97. doi: 10.7326/M15-0420. Epub 2015 Sep 29. PMID:26414147

Stoler MH, Ronnett BM, Joste NE, Hunt WC, Cuzick J, Wheeler CM; New MexicoHPVPapRegistry Steering Committee.  Am J Surg Pathol. 2015 Jun;39(6):729-36. doi: 10.1097/PAS.0000000000000381. PMID:25602796  

Cuzick J, Myers O, Hunt WC, Saslow D, Castle PE, Kinney W, Waxman A, Robertson M, Wheeler CM; New MexicoHPVPapRegistry Steering Committee.  Int J Cancer. 2015 Jun 15;136(12):2854-63. doi: 10.1002/ijc.29337. Epub 2014 Dec 1. PMID:25447979 

Joste NE, Ronnett BM, Hunt WC, Pearse A, Langsfeld E, Leete T, Jaramillo M, Stoler MH, Castle PE, Wheeler CM; New MexicoHPVPapRegistry Steering Committee.  Cancer Epidemiol Biomarkers Prev. 2015 Jan;24(1):230-40. doi: 10.1158/1055-9965.EPI-14-0775. Epub 2014 Nov 2. PMID:25363635

Castle PE, Hunt WC, Langsfeld E, Wheeler CM; New MexicoHPVPapRegistry Steering Committee.  Obstet Gynecol. 2014 Jan;123(1):49-56. doi: 10.1097/AOG.0000000000000013. PMID:24463663

Kinney W, Hunt WC, Dinkelspiel H, Robertson M, Cuzick J, Wheeler CM; New MexicoHPVPapRegistry Steering Committee.  Gynecol Oncol. 2014 Mar;132(3):628-35. doi: 10.1016/j.ygyno.2013.12.037. Epub 2014 Jan 4. PMID:24395062 

Cuzick J, Myers O, Hunt WC, Robertson M, Joste NE, Castle PE, Benard VB, Wheeler CM; New MexicoHPVPapRegistry Steering Committee.  Cancer Epidemiol Biomarkers Prev. 2014 May;23(5):765-73. doi: 10.1158/1055-9965.EPI-13-0973. Epub 2013 Dec 3. PMID:24302677 

Wheeler CM, Hunt WC, Cuzick J, Langsfeld E, Robertson M, Castle PE; New MexicoHPVPapRegistry Steering Committee.  Int J Cancer. 2014 Aug 1;135(3):624-34. doi: 10.1002/ijc.28605. Epub 2014 Apr 15.  PMID:24226935 

Wentzensen N, Nason M, Schiffman M, Dodd L, Hunt WC, Wheeler CM; New MexicoHPVPapRegistry Steering Committee.  J Infect Dis. 2014 Mar;209(6):855-64. doi: 10.1093/infdis/jit577. Epub 2013 Oct 31. PMID:24179110 

Gage JC, Joste N, Ronnett BM, Stoler M, Hunt WC, Schiffman M, Wheeler CM.  Hum Pathol. 2013 Nov;44(11):2542-8. doi: 10.1016/j.humpath.2013.06.015. Epub 2013 Sep 25. PMID: 24075599 

Gage JC, Schiffman M, Hunt WC, Joste N, Ghosh A, Wentzensen N, Wheeler CM; New MexicoHPVPapRegistry Steering Committee.  Am J Clin Pathol. 2013 Mar;139(3):330-5. doi: 10.1309/AJCPSD3ZXJXP7NNB. PMID: 23429369 

Wheeler CM, Hunt WC, Cuzick J, Langsfeld E, Pearse A, Montoya GD, Robertson M, Shearman CA, Castle PE; New MexicoHPVPapRegistry Steering Committee.  Int J Cancer. 2013 Jan 1;132(1):198-207. doi: 10.1002/ijc.27608. Epub 2012 Jun 20. PMID:22532127